antagonism

/æntˈægʌnɪzʌm/

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Definitions

Noun
a state of deep-seated ill-will
Noun
the relation between opposing principles or forces or factors; "the inherent antagonism of capitalism and socialism"
Noun
an actively expressed feeling of dislike and hostility
Noun
(biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure